90+ meta-analyses · 90+ interventions · 35+ countries

Evidence-Based Interventions
for Schizophrenia

See what works for schizophrenia. Every intervention is set against any reference intervention across efficacy, relapse, functioning and tolerability, and graded by the certainty of the evidence.

Or jump straight to a category

The EBI-SCZ evidence matrix: antipsychotics against placebo across efficacy and tolerability outcomes, graded by certainty.

Developed by

University of Ottawa

Rigorous evidence, transparently synthesized.

EBI-SCZ follows the U-REACH framework to identify, appraise and synthesize the best available evidence from network meta-analyses and umbrella reviews.

Learn about U-REACH
  1. 01

    Identify

    Systematically search peer-reviewed meta-analyses across all major databases.

  2. 02

    Appraise

    Assess methodological quality and rate the certainty of evidence with GRADE.

  3. 03

    Synthesize

    Combine findings across reviews and present them in a transparent, comparable matrix.

Built by researchers

EBI-SCZ pairs clinical and thematic expertise in psychosis with a dedicated evidence-synthesis methodology.

Thematic leadership

Marco Solmi

Marco Solmi

Clinical & thematic lead

Ana Catalán

Ana Catalán

Clinical & thematic lead

Methodology

Corentin J. Gosling

Corentin J. Gosling

Methodology & evidence synthesis

Samuele Cortese

Samuele Cortese

Methodology & evidence synthesis

Richard Delorme

Richard Delorme

Methodology & evidence synthesis

Marco Solmi

Marco Solmi

Methodology & evidence synthesis

Funded by
University of Ottawa

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